Development of medicinal products DUOFAG® and TRIOFAG® based on safe and effective bacteriophages

Identification code: CZ.01.01.01/01/24_063/0006534

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Provider: Ministry of Industry and Trade of the Czech Republic

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Programme: Operational Programme Technology and Application for Competitiveness

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Call: Application – DEEP TECH – Call III

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The project aims to develop and clinically test innovative bacteriophage-based medicines — DUOFAG® for treating postoperative wound infections caused by Staphylococcus aureus and Pseudomonas aeruginosa, and TRIOFAG® for respiratory infections caused by Acinetobacter baumannii, Klebsiella pneumoniae, and Staphylococcus aureus. Falling within the Deep Tech field of biotechnological development and production, the project will deliver two functional prototypes — a sterile wound-treatment solution (DUOFAG®) for phase IIa clinical trials and a liquid respiratory solution (TRIOFAG®) for phase I trials — as well as two pilot-scale GMP production units compliant with EMA and SÚKL standards.